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Meclizine
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
HRH1
TCF3
NFRKB
LDHB
TP53I11
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Pathway Enrichment
Most Correlated Biogroups
GSE45739_NRAS_KO_VS_WT_UNSTIM_CD4_TCELL_UP
CHEN_HOXA5_TARGETS_9HR_UP
positive regulation of blood circulation
HALLMARK_INFLAMMATORY_RESPONSE
WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_DN
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Curated Studies
Most Correlated Studies
Drug target sets for approved compounds
Broad Connectivity Map (CMAP 2.0) compound database
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
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Literature
Most Relevant Literature
Meclizine metabolism and pharmacokinetics: formulation on its absorption.
Meclizine is neuroprotective in models of Huntington's disease.
Differential effect of meclizine on the activity of human pregnane X receptor and constitutive andro…
Quantification of meclizine in human plasma by high performance liquid chromatography-mass spectrome…
Biphasic dosing regimen of meclizine for prevention of postoperative nausea and vomiting in a high-r…
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Clinical Trials
Most Relevant Clinical Trials
Meclizine for Hepatocellular Carcinoma
Meclizine Plasma Levels in Responders and Non-responders
Meclizine as a Potential Smoking Cessation Treatment
Evaluation of Meclizine Orodispersible Tablet Pharmacokinetic in Human Volunteers
Non Inferiority of Meclin® (Meclizine Chlorhydrate) Versus Dramin® (Dimenhydrinate) in Control of Ac…
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