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NAV1 1
Summary
General Info
Curated Studies
Most Correlated Studies
Zebrafish larvae with Scn1a (Nav1.1) mutation
Dorsal root ganglia from NAV1.7, NAV1.8 and NAV1.9 knockout mice
Dorsal root ganglia after diphtheria-toxin deletion of the Nav1.8-expressing cells
Dorsal root ganglia expression profiles in a neuropathic pain model - Davis-Tabor and Scott 2006
Nociceptors from jugular-nodose complex of mice with OVA allergic airway inflammation (AAI)
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Literature
Most Relevant Literature
Genetic and Functional Differences between Duplicated Zebrafish Genes for Human SCN1A.
CRISPRa-Mediated Upregulation of scn1laa During Early Development Causes Epileptiform Activity and d…
SCN1A overexpression, associated with a genomic region marked by a risk variant for a common epileps…
SCN1A intronic variants impact on Nav1.1 protein expression and sodium channel function, and associa…
Lasting effects of mild embryonic ethanol exposure on voltage-gated ion channels in adult zebrafish …
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Clinical Trials
Most Relevant Clinical Trials
Carbamazapine for Inherited Erythromelalgia Patients With NaV1.7 Mutations
Safety and Tolerability of Lacosamide in Patients With Gain-of-function Nav1.7 Mutations Related Sma…
An Open-Label Study to Investigate the Safety of Single and Multiple Ascending Doses in Children and…
An Open-Label Extension Study of STK-001 for Patients With Dravet Syndrome
Brugada Syndrome and Artificial Intelligence Applications to Diagnosis
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