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QuickView for NPM1 (gene)


Body Atlas

Most Correlated Tissues

  1. Granulocyte-macrophage progenitor cell of bone marrow
  2. Hematopoietic stem cell of bone marrow
  3. T Lymphocyte (regulatory) of peripheral blood
  4. Parotid gland
  5. Peritoneum
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Disease Atlas

Most Correlated Diseases

  1. Hepatocellular dysplasia
  2. Bacterial pneumonia
  3. Injury of eye region
  4. Human immunodeficiency virus infection
  5. Disease due to Lentivirus
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Pharmaco Atlas

Most Correlated Compounds

  1. 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane
  2. tetrabrominated diphenyl ether 47
  3. Methiocarb
  4. calycanthine
  5. 1-amino-2,4-dibromoanthraquinone
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. NPM1
  2. H2-Eb2
  3. Idd1
  4. Idd5
  5. SMIM26
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. Recent advances in AML with mutated NPM1.
  2. X-ray-downregulated nucleophosmin induces abnormal polarization by anchoring to G-actin.
  3. NPM1-Mutated Acute Myeloid Leukemia: Recent Developments and Open Questions.
  4. Targeting and Monitoring Acute Myeloid Leukaemia with Nucleophosmin-1 (NPM1) Mutation.
  5. Nucleophosmin 1 promotes mucosal immunity by supporting mitochondrial oxidative phosphorylation and …
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Clinical Trials

Most Relevant Clinical Trials

  1. Oral Arsenic Trioxide for NPM1-mutated AML
  2. Outcome of Patients With CBF and/or NPM1-mutated AML in First Molecular Relapse.
  3. Venetoclax Plus Azacitidine Versus Intensive Chemotherapy for Fit Patients With Newly Diagnosed NPM1…
  4. Venetoclax and Azacitidine for the Management of Molecular Relapse/Progression in Adult NPM1-mutated…
  5. A Study of DSP-5336 in Relapsed/Refractory AML/ ALL With or Without MLL Rearrangement or NPM1 Mutati…
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