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QuickView for NPM1 (gene)


Body Atlas

Most Correlated Tissues

  1. Granulocyte-macrophage progenitor cell of bone marrow
  2. Hematopoietic stem cell of bone marrow
  3. T Lymphocyte (regulatory) of peripheral blood
  4. Parotid gland
  5. Peritoneum
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Disease Atlas

Most Correlated Diseases

  1. Hepatocellular dysplasia
  2. Bacterial pneumonia
  3. Injury of eye region
  4. Human immunodeficiency virus infection
  5. Perforation of tympanic membrane
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Pharmaco Atlas

Most Correlated Compounds

  1. 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane
  2. tetrabrominated diphenyl ether 47
  3. Methiocarb
  4. 1-amino-2,4-dibromoanthraquinone
  5. 4,4-difluoro-5,7-dimethyl-4-bora-3a,4a-diaza-s-indacene-3-propionyl ethylene diamine
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. H2-Eb2
  2. Idd1
  3. Idd5
  4. HES3
  5. SMIM26
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. Type C mutation of nucleophosmin 1 acute myeloid leukemia: Consequences of intrinsic disorder.
  2. Nucleophosmin 1: from its pathogenic role to a tantalizing therapeutic target in acute myeloid leuke…
  3. NPM1 promotes cell proliferation by targeting PRDX6 in colorectal cancer.
  4. NPM1 ablation induces HSC aging and inflammation to develop myelodysplastic syndrome exacerbated by …
  5. NPM1 is a diagnostic and prognostic biomarker associated with the clinicopathological characteristic…
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Clinical Trials

Most Relevant Clinical Trials

  1. Oral Arsenic Trioxide for NPM1-mutated AML
  2. Outcome of Patients With CBF and/or NPM1-mutated AML in First Molecular Relapse.
  3. Venetoclax and Azacitidine for the Management of Molecular Relapse/Progression in Adult NPM1-mutated…
  4. A Study of DSP-5336 in Relapsed/Refractory AML/ ALL With or Without MLL Rearrangement or NPM1 Mutati…
  5. Study of BMF-219, a Covalent Menin Inhibitor, in Adult Patients With AML, ALL With KMT2A/ MLL1r, NPM…
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