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Notch1
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Summary
General Info
Body Atlas
Most Correlated Tissues
Neutrophil of bone marrow
Leukocyte (polymorphonuclear) of peripheral blood
Macrophage of peripheral blood
Eosinophil of peripheral blood
Whole blood
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Disease Atlas
Most Correlated Diseases
Heart valve disorder
Periodontitis
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Cancer of thymus
Tinea pedis
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Tramadol
styrene oxide
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SU 5416
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Most Correlated Gene Perturbations
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KMT5A
NOTCH1
MC1R
RPS6
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Curated Studies
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Literature
Most Relevant Literature
NOTCH1 Mutations Inhibit Tumor Growth in the Esophageal Epithelium.
NOTCH1-Related Leukoencephalopathy: A Novel Variant and Literature Review.
CAD204520 Targets NOTCH1 PEST Domain Mutations in Lymphoproliferative Disorders.
Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth.
NOTCH1 loss of the TAD and PEST domain: An antimorph?
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Clinical Trials
Most Relevant Clinical Trials
Zanubrutinib in Patients With DLBCL and MYD88 or NOTCH1 Mutation or CD5+
Rg3 in Combination With TACE in Hepatocellular Carcinoma Patients With High Expression of Notch1
Single-arm Study With Bimiralisib in Patients With HNSCC Harboring NOTCH1 Loss of Function Mutations
DNA Analysis of Tissue From Patients With T-Cell Acute Lymphoblastic Leukemia
Investigation of Patients With BAV Requiring Valve and/or Aortic Repair (GISSI Outliers VAR)
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