QuickView for OPTN;jsessionid=005971FBE9928DAC8897112ECFE42B2E;jsessionid=B74A72D802DDDACFBAB88941AF5E7C46;jsessionid=6912787DDA4D4C6D1953247C1FD55B8E (gene)

Summary
General Info

Body Atlas

Most Correlated Tissues

Skeletal muscle psoas
Skeletal muscle
T Lymphocyte (regulatory) of peripheral blood
Jejunum
Extraocular muscle

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Disease Atlas

Most Correlated Diseases

Ulceration of intestine
Glaucoma
Exercise
Neuropathy
Cutaneous acariasis

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Pharmaco Atlas

Most Correlated Compounds

Human Immunodeficiency Virus Proteins
Ceftazidime
STI571
Phorbol Esters
Fursultiamin

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Knockdown Atlas

Most Correlated Gene Perturbations

BTNL2
MAP4K4
GHR
CLK3
PROCR

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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

Deciphering the mitophagy receptor network identifies a crucial role for OPTN (optineurin) in acute …
OPTN attenuates the neurotoxicity of abnormal Tau protein by restoring autophagy.
OPTN (optineurin)-mediated selective autophagy prevents neurodegeneration due to herpesvirus infecti…
Optineurin regulates NRF2-mediated antioxidant response in a mouse model of Paget's disease of bone.
Optineurin deficiency impairs autophagy to cause interferon beta overproduction and increased surviv…

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Clinical Trials

Most Relevant Clinical Trials

There were no clinical trials for OPTN;jsessionid=005971FBE9928DAC8897112ECFE42B2E;jsessionid=B74A72D802DDDACFBAB88941AF5E7C46;jsessionid=6912787DDA4D4C6D1953247C1FD55B8E

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