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QuickView for PAK4 (gene)
Most Relevant Literature
- p21-activated kinase 4 counteracts PKA-dependent lipolysis by phosphorylating FABP4 and HSL.
- PAK4 phosphorylates and inhibits AMPKα to control glucose uptake.
- Interaction between p21-activated kinase 4 and β-catenin as a novel pathway for PTH-dependent osteob…
- PAK4 inhibition improves PD1 blockade immunotherapy in prostate cancer by increasing immune infiltra…
- p21-activated kinase 4 suppresses fatty acid β-oxidation and ketogenesis by phosphorylating NCoR1.
Most Relevant Clinical Trials
- A Study of Evaluating Dual Inhibitor of PAK4 and NAMPT ATG-019 in Advanced Solid Tumors or Non-Hodgk…
- PAK4 and NAMPT in Patients With Solid Malignancies or NHL (PANAMA)
- KPT-9274 in Patients With Relapsed and Refractory Acute Myeloid Leukemia
- This Is The First Study Using Escalating Doses Of PF-03758309, An Oral Compound, In Patients With Ad…
