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PFIC2
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Summary
General Info
Body Atlas
Most Correlated Tissues
Eosinophil of peripheral blood
Liver
Basophil of peripheral blood
Colon mucosa
Natural killer cell of peripheral blood
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Disease Atlas
Most Correlated Diseases
Cholestasis
Bacterial infection due to Bacillus
Liver transplant disorder
Infection by Schistosoma
Finding related to sleep
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Pharmaco Atlas
Most Correlated Compounds
Taurocholic Acid, Monosodium Salt
brivanib alaninate
presurface protein 1, hepatitis B surface antigen
GW 4064
Enterotoxins
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Knockdown Atlas
Most Correlated Gene Perturbations
PRRX2
CIT
NR1H4
CYP26B1
IKZF3
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Curated Studies
Most Correlated Studies
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Literature
Most Relevant Literature
miR-199a-5p inhibits the expression of ABCB11 in obstructive cholestasis.
Pharmacological Premature Termination Codon Readthrough of ABCB11 in Bile Salt Export Pump Deficienc…
Cell-based BSEP trans-inhibition: A novel, non-invasive test for diagnosis of antibody-induced BSEP …
Estrogen and Estrogen Receptor-α-Mediated Transrepression of Bile Salt Export Pump.
Antisense oligonucleotides rescue an intronic splicing variant in the ABCB11 gene that causes progre…
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Clinical Trials
Most Relevant Clinical Trials
This Study Will Investigate the Efficacy and Safety of A4250 in Children With PFIC 1 or 2
A Placebo-controlled Study of Maralixibat (SHP625) in Pediatric Subjects With Progressive Familial I…
NAtural Course and Prognosis of PFIC and Effect of Biliary Diversion
A Study of TAK-625 for the Treatment of Progressive Familial Intrahepatic Cholestasis (PFIC)
A Study to Evaluate the Efficacy and Safety of Maralixibat in Subjects With Progressive Familial Int…
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