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QuickView for PTEN (gene)


Body Atlas

Most Correlated Tissues

  1. Cerebellar hemisphere
  2. Leukocyte (polymorphonuclear) of peripheral blood
  3. Cerebellar vermis
  4. Cerebellum
  5. Peritoneum
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Disease Atlas

Most Correlated Diseases

  1. VATER association
  2. Macrocephaly
  3. Bacterial infection due to Bacillus
  4. Disease caused by parasite
  5. Brain cancer
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Pharmaco Atlas

Most Correlated Compounds

  1. CCI 779
  2. Extracellular Matrix Proteins
  3. benazepril
  4. 2-(4-(pyridin-4-yl-1-(2,2,2-trifluoroethyl)-1H-pyrazol-3-yl)phenoxymethyl)quinoline succinic acid
  5. Chlormezanone
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. Jak2
  2. OMD
  3. MOS
  4. B2M
  5. FGFR1
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. Chemotherapy-induced PTEN-L secretion promotes the selection of PTEN-deficient tumor cells.
  2. Decoding PTEN: from biological functions to signaling pathways in tumors.
  3. PTEN: an emerging target in rheumatoid arthritis?
  4. High glucose-induced downregulation of PTEN-Long is sufficient for proximal tubular cell injury in d…
  5. Investigating the effects of PTEN mutations on cGAS-STING pathway in glioblastoma tumours.
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Clinical Trials

Most Relevant Clinical Trials

  1. Partial PTEN Deletion in Breast Cancer
  2. Access to Resources for Patients With PTEN Hamartoma Tumor Syndrome
  3. TAS-117 in Patients With Advanced Solid Tumors Harboring Germline PTEN Mutations
  4. Development and Validation of an Online Neurobehavioral Evaluation Tool for PTEN Patients
  5. RAD001 and Neurocognition in PTEN Hamartoma Tumor Syndrome
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