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PU 1
Summary
General Info
Curated Studies
Most Correlated Studies
Double negative T cells overexpressing PU.1-ETS domain or PU.1-ETS-EN1 fusion proteins
Myeloid progenitor PU.1 null cell line differentiation via a tamoxifen-induced ER-PU.1 transgene
Hematopoietic stem cell proliferation in PU.1 knockin mice
Bone marrow FDCP-mix cells depleted of Gata2 or Pu.1
Bone marrow FDCP-mix cells conditionally overexpressing Gata1 or Pu.1
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Literature
Most Relevant Literature
Combined Approach to Leukemic Differentiation Using Transcription Factor PU.1-Enhancing Agents.
Blood stem cell PU.1 upregulation is a consequence of differentiation without fast autoregulation.
Intracellular Salmonella Paratyphi A is motile and differs in the expression of flagella-chemotaxis,…
Transcription factor PU.1 and immune cell differentiation (Review).
PU.1-Dependent Enhancer Inhibition Separates Tet2-Deficient Hematopoiesis from Malignant Transformat…
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Clinical Trials
Most Relevant Clinical Trials
FoxO3a and PU.1 in Acute Lymphoblastic Leukemia
PET Imaging of Subjects Using 124I-PU-AD
A Single and Multiple Ascending Dose Study to Evaluate the Safety and Pharmacokinetics of PU-AD in H…
Evaluation of Ruxolitinib in Combination With PU-H71 for Treatment of Myelofibrosis
To Evaluate Safety, Tolerability and Pharmacological Effects of PU AD in Subjects With Mild AD Demen…
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