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Sirolimus
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Summary
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Genetic Markers
Most Correlated Genes
XIST
NPR3
MAL
SERPINA3
WIF1
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Pathway Enrichment
Most Correlated Biogroups
organic cyclic compound binding
heterocyclic compound binding
organic cyclic compound metabolic process
heterocycle metabolic process
PUJANA_BRCA1_PCC_NETWORK
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Curated Studies
Most Correlated Studies
Glucocorticoid resistance in acute lymphoblastic leukemia and rapamycin in resistance reversal
Structure and function of kidney transplant without calcineurin inhibitors
S.cerevisiae strain specific gene expression in response to arsenic stree
MRC-5 Lung fibroblast cells treated with rapamycin to study alternative translational routes
Transcriptional response to nitrogen availability in yeast
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Literature
Most Relevant Literature
Targeting ageing with rapamycin and its derivatives in humans: a systematic review.
TFEB drives mTORC1 hyperactivation and kidney disease in Tuberous Sclerosis Complex.
mTORC1 regulates the metabolic switch of postnatal cardiomyocytes during regeneration.
Sirolimus-loaded exosomes as a promising vascular delivery system for the prevention of post-angiopl…
Polyploidy and mTOR signaling: a possible molecular link.
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Clinical Trials
Most Relevant Clinical Trials
Sirolimus for the Treatment of Hyperinsulinism
Sirolimus for Autoimmune Disease of Blood Cells
Sirolimus Use in Angioplasty for Vascular Access Extension
Sirolimus and Cetuximab in Advanced Malignancies
Lapatinib With Sirolimus or Metformin
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