QuickView for Smc5;jsessionid=D62A2934A82137D2D2835712EB4A1230;jsessionid=4BF2A791D7645FB57242E8C40E2A88D1;jsessionid=25B94E7B03A1B9AC0BF20831F5CBE3E6;jsessionid=F77BF7891788AA94BD3C8811DACA5C4F;jsessionid=E07647318AC90F5DAA90D2698880652D;jsessionid=BE109AEDA040E678E1F2486D35997632 (gene)

1. Human Smc5/6 recognises transcription-generated positive DNA supercoils.
2. Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms.
3. SMC5 Plays Independent Roles in Congenital Heart Disease and Neurodevelopmental Disability.
4. The SMC5/6 complex prevents genotoxicity upon APOBEC3A-mediated replication stress.
5. Crucial role of the NSE1 RING domain in Smc5/6 stability and FANCM-independent fork progression.

There were no clinical trials for Smc5;jsessionid=D62A2934A82137D2D2835712EB4A1230;jsessionid=4BF2A791D7645FB57242E8C40E2A88D1;jsessionid=25B94E7B03A1B9AC0BF20831F5CBE3E6;jsessionid=F77BF7891788AA94BD3C8811DACA5C4F;jsessionid=E07647318AC90F5DAA90D2698880652D;jsessionid=BE109AEDA040E678E1F2486D35997632