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QuickView for TIE1 (gene)


Body Atlas

Most Correlated Tissues

  1. Omental adipose tissue
  2. Lung
  3. Fetal lung
  4. Heart ventricle
  5. Adipose tissue subcutaneous
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Disease Atlas

Most Correlated Diseases

  1. 11p partial monosomy syndrome
  2. Lymphedema
  3. Lung cancer
  4. Musculoskeletal function
  5. Viral carditis
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Pharmaco Atlas

Most Correlated Compounds

  1. SB 202190
  2. HGF protein, human
  3. tat Gene Products, Human Immunodeficiency Virus
  4. Thimerosal
  5. phorbolol-12-myristate-13-acetate
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. Tnfaip6
  2. ZSCAN25
  3. SOX6
  4. RNR1
  5. FOXF2
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. TIE1 promotes cervical cancer progression via Basigin-matrix metalloproteinase axis.
  2. Loss-of-function mutations of the TIE1 receptor tyrosine kinase cause late-onset primary lymphedema.
  3. Svep1 is a binding ligand of Tie1 and affects specific aspects of facial lymphatic development in a …
  4. A novel cis-regulatory variant modulating TIE1 expression associated with attention deficit hyperact…
  5. Polydom/SVEP1 binds to Tie1 and promotes migration of lymphatic endothelial cells.
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Clinical Trials

Most Relevant Clinical Trials

  1. A Study to Evaluate the Safety and Antitumor Activity in Subjects With Advanced Solid Tumors
  2. Phase I Clinical Trial of Tremelimumab Plus MEDI3617 in Patients With Unresectable Stage III or Stag…
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