QuickView for TPKC1;jsessionid=6E914B61358162D1F9E976FF07D4FD40;jsessionid=7550C530B68131287A0834DFC8F78927;jsessionid=2F6F503FCCB6EC4EA2F8E9202E94F5B2;jsessionid=C79EAAA8FA183B983965CCA6DE2AB182 (gene)

1. TREK-1 inhibition promotes synaptic plasticity in the prelimbic cortex.
2. Tension activation of mechanosensitive two-pore domain K+ channels TRAAK, TREK-1, and TREK-2.
3. Novel potent blockers for TWIK-1/TREK-1 heterodimers as potential antidepressants.
4. Production of K2P2.1 (TREK-1) for structural studies.
5. Two-pore potassium channel TREK-1 (K2P2.1) regulates NLRP3 inflammasome activity in macrophages.

There were no clinical trials for TPKC1;jsessionid=6E914B61358162D1F9E976FF07D4FD40;jsessionid=7550C530B68131287A0834DFC8F78927;jsessionid=2F6F503FCCB6EC4EA2F8E9202E94F5B2;jsessionid=C79EAAA8FA183B983965CCA6DE2AB182