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QuickView for TREM2 (gene)


Body Atlas

Most Correlated Tissues

  1. Microglial cell
  2. Skeletal muscle psoas
  3. Olfactory bulb
  4. Tongue
  5. Nodose nucleus
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Disease Atlas

Most Correlated Diseases

  1. Bone cyst
  2. High fat diet
  3. Stachybotryotoxicosis
  4. Injury of external ear
  5. Ischemia
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Pharmaco Atlas

Most Correlated Compounds

  1. Bleomycin
  2. Sodium Butyrate
  3. Quercetin
  4. Smoke
  5. Chemokine CCL17
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. TREM2
  2. PSEN1
  3. FEN1
  4. CCNT1
  5. RTN4
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. Trem2 expression in microglia is required to maintain normal neuronal bioenergetics during developme…
  2. Targeting TREM2 signaling shows limited impact on cerebrovascular calcification.
  3. Trem2 H157Y increases soluble TREM2 production and reduces amyloid pathology.
  4. Cannabis Use and Cannabidiol Modulate HIV-Induced Alterations in TREM2 Expression: Implications for …
  5. TREM-2 Drives Development of Multiple Sclerosis by Promoting Pathogenic Th17 Polarization.
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Clinical Trials

Most Relevant Clinical Trials

  1. The Analysis of Gene Variants Related to POCD in Elderly Patients
  2. A Study of PY314 in Subjects With Advanced Solid Tumors
  3. Gut Microbiota and Parkinson's Disease
  4. Simufilam (PTI-125), 100 mg, for Mild-to-moderate Alzheimer's Disease Patients
  5. Randomized I/II Phase Study of ALZT-OP1 Combination Therapy in Alzheimer's Disease and Normal Health…
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