QuickView for UBA2;jsessionid=12D6DDF8A7D0CD64B1FDE615CC20867E (gene)

1. Nej1 interacts with Sae2 at DNA double-stranded breaks to inhibit DNA resection.
2. Sir3 heterochromatin protein promotes non-homologous end joining by direct inhibition of Sae2.
3. Sae2 and Rif2 regulate MRX endonuclease activity at DNA double-strand breaks in opposite manners.
4. Interplay between Sae2 and Rif2 in the regulation of Mre11-Rad50 activities at DNA ends.
5. Regulatory control of DNA end resection by Sae2 phosphorylation.

There were no clinical trials for UBA2;jsessionid=12D6DDF8A7D0CD64B1FDE615CC20867E