QuickView for VIPAS39;jsessionid=0CF5A874DF2934760E6F086585536C4C (gene)

1. The Sec1-Munc18 protein VPS33B forms a uniquely bidirectional complex with VPS16B.
2. Platelet VPS16B is dependent on VPS33B expression, as determined in two siblings with arthrogryposis…
3. Vps33b pathogenic mutations preferentially affect VIPAS39/SPE-39-positive endosomes.
4. Inhibitory effect of SPE-39 due to tyrosine phosphorylation and ubiquitination on the function of Vp…
5. The VPS33B-binding protein VPS16B is required in megakaryocyte and platelet α-granule biogenesis.

There were no clinical trials for VIPAS39;jsessionid=0CF5A874DF2934760E6F086585536C4C