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Xeroderma pigmentosum, group A
(phenotype)
Summary
General Info
Genetic Markers
Most Correlated Genes
Most Correlated SNPs
XPA
No SNPs found
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Pathway Enrichment
Most Correlated Biogroups
XPA, C-terminal
Zinc finger, XPA-type, conserved site
XPA
XPA, conserved site
nucleotide-excision repair involved in interstrand cross-link repair
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Curated Studies
Most Correlated Studies
OMIM - Xeroderma pigmentosum
Skin fibroblasts and cervical cancer cells with deficient XPA treated with all-trans retinoic acid
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Literature
Most Relevant Literature
XPA Enhances Temozolomide Resistance of Glioblastoma Cells by Promoting Nucleotide Excision Repair.
XPA is susceptible to proteolytic cleavage by cathepsin L during lysis of quiescent cells.
Probing Protein-DNA Conformational Dynamics in DNA Damage Recognition: Xeroderma Pigmentosum Group A…
XPA: DNA Repair Protein of Significant Clinical Importance.
Meta-analysis on the association between xeroderma pigmentosum Group A A23G polymorphism and esophag…
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Clinical Trials
Most Relevant Clinical Trials
T4N5 Liposome Lotion Compared With Placebo Lotion for Preventing Actinic Keratoses in Patients With …
Examination of Clinical and Laboratory Abnormalities in Patients With Defective DNA Repair: Xeroderm…
A Study to Evaluate the Safety and Efficacy of Afamelanotide in Patients With Xeroderma Pigmentosum …
A Study to Evaluate the Safety and Efficacy of Afamelanotide in Patients With Xeroderma Pigmentosum …
Use of an SPF30 Sunscreen and an After-sun-lotion in Skin Cancer Risk Patients
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