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QuickView for abt 263 (compound)


Genetic Markers

Most Correlated Genes

  1. No genes found
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Pathway Enrichment

Most Correlated Biogroups

  1. No biogroups found
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Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
  2. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
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Literature

Most Relevant Literature

  1. Senolysis by ABT-263 is associated with inherent apoptotic dependence of cancer cells derived from t…
  2. Topical ABT-263 treatment reduces aged skin senescence and improves subsequent wound healing.
  3. Topical ABT-263 treatment reduces aged skin senescence and improves subsequent wound healing.
  4. Treatment of advanced atherosclerotic mice with ABT-263 reduced indices of plaque stability and incr…
  5. The senolytic drug ABT-263 accelerates ovarian aging in older female mice.
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Clinical Trials

Most Relevant Clinical Trials

  1. Safety Study of ABT-263 in Combination With Rituximab in Lymphoid Cancers
  2. Assess the Oral Bioavailability of New ABT-263 Formulations
  3. A Study to Assess the Effect of Ketoconazole on the Metabolism of ABT-263 (Navitoclax).
  4. A Study of ABT-263 in Subjects With Relapsed or Refractory Lymphoid Malignancies
  5. Assess the Oral Bioavailability of a New ABT-263 Formulation in Healthy Female Subjects
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