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amn107
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Summary
General Info
Genetic Markers
Most Correlated Genes
No genes found
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Pathway Enrichment
Most Correlated Biogroups
No biogroups found
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Curated Studies
Most Correlated Studies
Embryonic fibroblasts of mice treated with BCR-ABL inhibitor AMN107 and IFN-alpha or IFN-gamma
Osteosarcoma U-2 OS cells treated with 6 different small molecules
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Literature
Most Relevant Literature
Endoplasmic reticulum stress-mediated apoptosis in imatinib-resistant leukemic K562-r cells triggere…
CML cell apoptosis induced by AMN107 combined with heme oxygenase-1 inhibitor].
A novel tyrosine kinase inhibitor AMN107 (nilotinib) normalizes striatal motor behaviors in a mouse …
Imatinib mesylate and AMN107 inhibit PDGF-signaling in orbital fibroblasts: a potential treatment fo…
Nonreceptor Tyrosine Kinase c-Abl- and Arg-Mediated IRF3 Phosphorylation Regulates Innate Immune Res…
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Clinical Trials
Most Relevant Clinical Trials
Study of AMN107 With Imatinib in Gastrointestinal Stromal Tumors (GIST)
Expanded Access Program of AMN107 in Imatinib-resistant or Intolerant Adult Patients With Chronic My…
A Study of Oral AMN107 in Adults With Chronic Myelogenous Leukemia (CML) or Other Blood Related Canc…
Efficacy and Safety of Oral AMN107 in Adults With Chronic Myelogenous Leukemia Resistant and/or Into…
Efficacy and Safety of AMN107 in Patients With GastroIntestinal Stromal Tumors (GIST) Who Have Faile…
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