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QuickView for angiotensin ii type 2 receptor blockers (compound)


Genetic Markers

Most Correlated Genes

  1. AGTR1
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Pathway Enrichment

Most Correlated Biogroups

  1. Angiotensin II receptor type 1
  2. phospholipase C-activating angiotensin-activated signaling pathway
  3. Angiotensin II receptor family
  4. SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX6_DN
  5. positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
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Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
  2. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
  3. Drug target sets for approved compounds
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Literature

Most Relevant Literature

  1. Non-clinical characterization of the disposition of EMA401, a novel small molecule angiotensin II ty…
  2. Attenuation of Unevoked Mechanical and Cold Pain Hypersensitivities Associated With Experimental Neu…
  3. Analgesic efficacy of small-molecule angiotensin II type 2 receptor antagonists in a rat model of an…
  4. The angiotensin II receptors type 1 and 2 modulate astrocytes and their crosstalk with microglia and…
  5. Analgesic efficacy and mode of action of a selective small molecule angiotensin II type 2 receptor a…
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Clinical Trials

Most Relevant Clinical Trials

  1. Angiotensin Receptor Blockers in Aortic Stenosis
  2. Renoprotection by Pentoxifylline and Angiotensin Receptor Blocker in Chronic Kidney Disease (CKD)
  3. Controlled evaLuation of Angiotensin Receptor Blockers for COVID-19 respIraTorY Disease
  4. Angiotensin II in Liver Transplantation
  5. New Angiotensin II Receptor Blocker Azilsartan Study for Stronger Blood Pressure Lowering
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