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QuickView for ccr4 protein, human (compound)


Genetic Markers

Most Correlated Genes

  1. No genes found
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Pathway Enrichment

Most Correlated Biogroups

  1. No biogroups found
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Curated Studies

Most Correlated Studies

  1. CD4+ T helper subsets; resistant or permissive to HIV infection
  2. DLBCL U-2932 cells expressing RC3H2 wildtype or RC3H2 Y691F mutation and treated with F(ab')2-IgM
  3. Acute lymphoblastic leukemia CCRF-CEM and Jurkat cells with CNOT3 siRNA and with actinomycin D
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Literature

Most Relevant Literature

  1. Clinical and molecular effects of oral CCR4 antagonist RPT193 in atopic dermatitis: A Phase 1 study.
  2. Small-Molecule CCR4 Antagonists in Cutaneous T-cell Lymphoma.
  3. Reconstitution of Human CCR4-NOT Complex from Purified Proteins and an Assay of Its Deadenylation Ac…
  4. Immune-related adverse events associated with mogamulizumab: a comprehensive review of the literatur…
  5. Failure of second challenge with mogamulizumab in C-C chemokine receptor 4-positive cutaneous T-cell…
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Clinical Trials

Most Relevant Clinical Trials

  1. Phase I Study of KW-0761 in Relapsed Patients With CCR4-Positive ATL and PTCL
  2. Implication of CCR4-NOT Complex Subunit 7 Expression in Natural Killer Cell Resistance in Metastatic…
  3. Study of KW-0761 (Mogamulizumab) in Subjects With Previously Treated Peripheral T-cell Lymphoma (PTC…
  4. Mogamulizumab and Extracorporeal Photopheresis for the Treatment of Sezary Syndrome or Mycosis Fungo…
  5. KHK2455 Alone and in Combination With Mogamulizumab in Subjects With Locally Advanced or Metastatic …
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