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entinostat
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
CFD
S100A2
NPR3
ANO1
CLIC3
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Pathway Enrichment
Most Correlated Biogroups
organic cyclic compound binding
heterocyclic compound binding
organic cyclic compound metabolic process
nucleoplasm
cellular aromatic compound metabolic process
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Curated Studies
Most Correlated Studies
Breast cancer MDA-MB-231 cells treated with combinations of entinostat, retinoic acid & doxorubicin
Neuroepithelial progenitors differentiated from ESCs and treated with toxicants
Diffuse intrinsic pontine glioma SU-DIPGXIII cells treated with compound 7, entinostat, or corin
Colorectal cancer HCT116 cells p53 WT or null treated with nutlin-3A, entinostat, or both
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
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Literature
Most Relevant Literature
Class I HDAC inhibitor entinostat synergizes with PLK1 inhibitors in MYC-amplified medulloblastoma c…
Topical histone deacetylase 1 inhibitor Entinostat ameliorates psoriasiform dermatitis through suppr…
Entinostat Decreases Immune Suppression to Promote Antitumor Responses in a HER2+ Breast Tumor Micro…
Phase I Study of Entinostat and Nivolumab with or without Ipilimumab in Advanced Solid Tumors (ETCTN…
Efficacy and exploratory biomarker analysis of entinostat plus exemestane in advanced or recurrent b…
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Clinical Trials
Most Relevant Clinical Trials
Entinostat Neuroendocrine (NE) Tumor
Combination of Entinostat and Enzalutamide in Advanced Prostate Cancer
Entinostat in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors
Study to Determine the Effect of the Timing of a Meal on the Pharmacokinetics of Entinostat
Azacitidine and Entinostat in Treating Patients With Metastatic Colorectal Cancer
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