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QuickView for factor VIII (compound)


Genetic Markers

Most Correlated Genes

  1. F10
  2. SPP1
  3. APOC1
  4. RAB3IL1
  5. EGR3
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Pathway Enrichment

Most Correlated Biogroups

  1. BROWN_MYELOID_CELL_DEVELOPMENT_UP
  2. GSE25085_FETAL_LIVER_VS_FETAL_BM_SP4_THYMIC_IMPLANT_DN
  3. GSE3039_CD4_TCELL_VS_B1_BCELL_DN
  4. RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP
  5. GSE9988_ANTI_TREM1_VS_VEHICLE_TREATED_MONOCYTES_UP
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Curated Studies

Most Correlated Studies

  1. Macrophages from monocytes of donors treated with FVIII or FVIII-Fc fusion protein
  2. Drug target sets for approved compounds
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Literature

Most Relevant Literature

  1. Natural and engineered mediators of desiccation tolerance stabilize Human Blood Clotting Factor VIII…
  2. Role of L-Arginine on the Expression of Coagulation Factor VIII Gene.
  3. Augmented Degradation of Factors VIII and IX in the Intermittent Movement State.
  4. Successful transfemoral prosthesis in a patient with haemophilia A and factor VIII inhibitors: A cas…
  5. Guidance for establishing a factor VIII testing protocol for the myriad of factor VIII products.
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Clinical Trials

Most Relevant Clinical Trials

  1. Improved Factor VIII Inhibitor Evaluation
  2. Activity and Content of Factor VIII (FVIII) in Human Plasma: The Assessment of a Novel Immunoassay
  3. Study of Recombinant Porcine Factor VIII (FVIII) in Hemophilia and Inhibitors to FVIII
  4. Hemophilia Adult Prophylaxis Study: Factor VIII in Severe Hemophilia A
  5. Gene Therapy Trial for Platelet Derived Factor VIII Production in Hemophilia A
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