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rs4950928
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ZBTB7A
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folate reductase activity
(biogroup)
Summary
General Info
Body Atlas
Most Correlated Tissues
Bone marrow
Adipose tissue subcutaneous
Trachea
Hematopoietic stem cell of bone marrow
Adipose tissue
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Disease Atlas
Most Correlated Diseases
Rhinitis
Zika virus disease
Gastrointestinal hemorrhage
Helicobacter pylori gastrointestinal tract infection
Gastritis
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Pharmaco Atlas
Most Correlated Compounds
Trimetrexate
pemetrexed
Isoleucine
Valine
clofilium
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Knockdown Atlas
Most Correlated Gene Perturbations
MIRLET7F1
DIS3L2
PNKP
ABCE1
PCDH11X
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Curated Studies
Most Correlated Studies
OMIM - Anemia disorders
L1000 CMAP Breast cancer MCF7 cells with gene overexpression perturbations
L1000 CMAP - Colorectal cancer DLD-1 cells with shRNA-mediated gene knockdown
Drug target sets for approved compounds
L1000 CMAP - Embryonic kidney epithelial HA1E cells treated with ligand perturbagens
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Literature
Most Relevant Literature
Genetic and metabolic analysis of folate salvage in the human malaria parasite Plasmodium falciparum…
The effect of folate antagonists on dihydrofolate reductase activity demonstrated cytochemically.
Hybridization of hamster cells with high and low folate reductase activity.
Resistance of Pediococcus cerevisiae to amethopterin as a consequence of changes in enzymatic activi…
Model for specific rescue of normal hepatocytes during methotrexate treatment of hepatic malignancy.
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Clinical Trials
Most Relevant Clinical Trials
A Study to Assess CH1504 in Patients With Active Rheumatoid Arthritis
RIBOGENE: Optimisation of Riboflavin Status in Hypertensive Adults With a Genetic Predisposition to …
Tumor Response to Pemetrexed Disodium in Patients With Stage III or Stage IV Non-Small Cell Lung Can…
DHFR 19 bp Deletion Polymorphism and Folic Acid Utilization
Blood Pressure Lowering Effect of B-vitamins in Adults With a Genetic Pre-disposition to Elevated Bl…
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