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Correlation Engine 2.0
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(e.g. NEUROG3, Coagulation, Hepatitis, Leukocyte, Avian flu virus, Lovastatin, rs3825942)
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QuickView for fumarate hydratase activity (biogroup)


Body Atlas

Most Correlated Tissues

  1. Heart atrium
  2. Heart
  3. Lung
  4. Tongue main corpus
  5. Heart ventricle
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Disease Atlas

Most Correlated Diseases

  1. Fumarase deficiency
  2. Sepsis due to coagulase negative Staphylococcus
  3. Disease due to Adenovirus
  4. Hypercholesterolemia
  5. Disorder related to transplantation
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Pharmaco Atlas

Most Correlated Compounds

  1. cinobufotalin
  2. telocinobufagin
  3. notoginsenoside R1
  4. scutellarein
  5. schizandrin
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. spi
  2. Mir10a
  3. SPINDOC
  4. PNKP
  5. LAT
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Curated Studies

Most Correlated Studies

  1. OMIM - Congenital disorder
  2. L1000 CMAP - Hepatocellular carcinoma Hep G2 cells with shRNA-mediated gene knockdown (2 of 2)
  3. L1000 CMAP - Amelanotic malignant melanoma of skin A375 cells treated with ligand perturbagens
  4. Cancer Gene Census - mutations in cancer genes
  5. L1000 CMAP Colorectal cancer HT 29 cells with gene overexpression perturbations
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Literature

Most Relevant Literature

  1. Fumarate hydratase gene mutation in two young patients with sporadic uterine fibroids.
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Clinical Trials

Most Relevant Clinical Trials

  1. Sintilimab Injection Combined With Inlyta in Fumarate Hydratase- Deficient Renal Cell Carcinoma
  2. Hereditary Leiomyomatosis Renal Cell Cancer - Study of the Genetic Cause and the Predisposition to R…
  3. A Phase II Trial of the DNA Methyl Transferase Inhibitor, Guadecitabine (SGI-110), in Children and A…
  4. A Study to Evaluate Efficacy and Safety of Lenvatinib Combined With Tislelizumab in Patients With FH…
  5. Sintilimab in FH-deficient Renal Cell Carcinoma
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