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Genetic Markers
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PDK4
Acot1
FOS
EGR1
ACOT2
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Pathway Enrichment
Most Correlated Biogroups
organic cyclic compound metabolic process
heterocyclic compound binding
heterocycle metabolic process
organic cyclic compound binding
PUJANA_BRCA1_PCC_NETWORK
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Curated Studies
Most Correlated Studies
Glioblastoma multiforme subtypes at resection with pre-operative therapies and clinical outcomes
Breast tumors with pathologic complete response (pCR) or residual disease (RD) upon chemotherapy
Bronchioepithelial cells exposed to a large dose range of N-hydroxylated PhIP
Cardiac gene expression regulated by single fatty acids in wildtype and PPARa null mice
Hepatocytes treated with non-genotoxic carcinogens
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Literature
Most Relevant Literature
Unboxing the molecular modalities of mutagens in cancer.
Delivery, structure, and function of bacterial genotoxins.
Microbiota-derived genotoxin tilimycin generates colonic stem cell mutations.
A small molecule inhibitor prevents gut bacterial genotoxin production.
Bacterial genotoxins induce TÂ cell senescence.
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Clinical Trials
Most Relevant Clinical Trials
Prospective Cohort Assessing the Role of the Genotoxin Colibactin From Escherichia Coli B2 in the Ge…
Determination of Microbiological Factors Associated With Poor Response to Neoadjuvant Treatment in R…
Diet Modulation of Bacterial Sulfur and Bile Acid Metabolism and Colon Cancer Risk
Faecal Microbiota Characterization in Lynch Syndrome (LS) Patients With or Without Colorectal Neopla…
Microbiota and Related Metabolome in Omnivore, Vegetarian or Vegan Diets
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