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interleukin 1 receptor antagonist protein
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
CXCL2
CCL2
CXCL6
AKR1B15
MCEMP1
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Pathway Enrichment
Most Correlated Biogroups
TRAVAGLINI_LUNG_OLR1_CLASSICAL_MONOCYTE_CELL
immune response
MANNO_MIDBRAIN_NEUROTYPES_HMGL
MURARO_PANCREAS_DUCTAL_CELL
response to stress
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Curated Studies
Most Correlated Studies
PBMCs cultured with sera with low or high IL-1ra from diabetic and healthy patients
Skin of neonatal-onset multisystem inflammatory disease (NOMID) before and after Kineret treatment
Monocyte-derived dendritic cells (DCs) treated with beta-glucan and IL-1RA
Peripheral blood mononuclear cells (PBMC) exposed to plasma of diabetes patients or healthy siblings
PBMCs from Schnitzler's syndrome patients treated with anakinra or canakinumab
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Literature
Most Relevant Literature
The role of alcohol use and adiposity in serum levels of IL-1RA in depressed patients.
Prenatal administration of IL-1Ra attenuate the neurodevelopmental impacts following non-pathogenic …
IL-1RA suppresses esophageal cancer cell growth by blocking IL-1α.
A metal-organic framework-based immunomodulatory nanoplatform for anti-atherosclerosis treatment.
Anakinra-Associated Systemic Amyloidosis.
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Clinical Trials
Most Relevant Clinical Trials
BLOC-ICH: Interleukin-1 Receptor Antagonist in Intracerebral Haemorrhage
GDM Patients and Serum Amyloid A and Interleukin-1 (IL-1) Receptor Antagonist
Interleukin-1 Receptor Antagonist and Insulin Sensitivity
Pilot Study of the Safety and Efficacy of Anakinra (Recombinant Human Interleukin-1 Receptor Antagon…
Pilot Study of the Safety and Efficacy of Anakinra (Recombinant Human Interleukin-1 Receptor Antagon…
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