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interleukin 12 subunit p40
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
IL2
TNFSF14
GZMB
MIPEP
SGSH
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Pathway Enrichment
Most Correlated Biogroups
GSE23114_WT_VS_SLE2C1_MOUSE_SPLEEN_B1A_BCELL_UP
GSE24574_BCL6_HIGH_TFH_VS_NAIVE_CD4_TCELL_DN
GSE26727_WT_VS_KLF2_KO_LPS_STIM_MACROPHAGE_DN
GSE28726_NAIVE_VS_ACTIVATED_CD4_TCELL_DN
PUJANA_CHEK2_PCC_NETWORK
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Curated Studies
Most Correlated Studies
Colons of MDR1A KO mice with Helicobacter bilis colitis treated with interleukin blocking antibodies
NK cell gene expression in response to activation by mycobacteria of differing virulence
Th1 or Th2 in the presence or absence of TGFbeta
L1000 CMAP - Colorectal cancer HT29 cells treated with ligand perturbagens
L1000 CMAP - Prostate carcinoma VCaP cells treated with ligand perturbagens
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Literature
Most Relevant Literature
Autosomal Recessive IL-12p40 Deficiency due to a Mutation in the IL12B Gene: Report of a Brazilian P…
Elimination of Chlamydia muridarum from the female reproductive tract is IL-12p40 dependent, but ind…
Single-Cell Analysis Reveals a Subset of High IL-12p40-Secreting Dendritic Cells within Mouse Bone M…
IL-12p40 promotes secondary damage and functional impairment after spinal cord contusional injury.
IL-12p40 is essential but not sufficient for Francisella tularensis LVS clearance in chronically inf…
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Clinical Trials
Most Relevant Clinical Trials
Ustekinumab (Anti-IL-12/23p40 Monoclonal Antibody) in Patients With Leukocyte Adhesion Deficiency Ty…
IL-10, IL-12 and IL-18 Levels in the Gingival Crevicular Fluid of Patients With Periodontitis and He…
Quantify the Value of Transmural Inflammation in the Treatment of Crohn's Disease With Ustekinumab:a…
Mechanism of Action of Ustekinumab in Psoriatic Arthritis
A Study of Mirikizumab (LY3074828) in Children and Teenagers With Ulcerative Colitis (UC)
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