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kinesins
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Curated Studies
Most Correlated Studies
Connective tissue fibrosarcoma HT-1080 cells with KIF20A gene knockdown
Prostate cancer C4-2B cells enzalutamide resistant with KIF15 siRNA knockdown
Taxane resistance in breast cancer after paclitaxel treatment
Manipulation of RNA helicase A and KIF1Bbeta in a neuroblastoma cell line
Naive and memory CD4+ T cells from healthy donors stimulated with anti-CD3 anti-CD28 antibodies
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Literature
Most Relevant Literature
De novo heterozygous variants in KIF5B cause kyphomelic dysplasia.
A role for kinesin-1 subunits KIF5B/KLC1 in regulating epithelial mesenchymal plasticity in breast t…
Dominant negative variants in KIF5B cause osteogenesis imperfecta via down regulation of mTOR signal…
Synergistic autoinhibition and activation mechanisms control kinesin-1 motor activity.
Concerted action of kinesins KIF5B and KIF13B promotes efficient secretory vesicle transport to micr…
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Clinical Trials
Most Relevant Clinical Trials
Open Label, Dose Escalation Trial of Oral Eg5 Kinesin-spindle Inhibitor 4SC-205 in Patients With Adv…
A Phase II Study of AZD4877 (a Novel Anti-mitotic Agent) in Advanced Bladder Cancer
Phase I, Open-label, Dose-escalation, Safety and PK Study of AZD4877
SB-715992 in Treating Patients With Metastatic or Recurrent Malignant Melanoma
SB-715992 in Treating Patients With Locally Advanced, Recurrent, or Metastatic Liver Cancer
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