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QuickView for kynureninase activities (biogroup)


Body Atlas

Most Correlated Tissues

  1. Microglial cell
  2. Myeloid cells of peripheral blood
  3. Fetal liver
  4. Bladder
  5. Monocyte of peripheral blood
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Disease Atlas

Most Correlated Diseases

  1. Hutchinson-Gilford syndrome
  2. Gastrointestinal hemorrhage
  3. Ulceration of intestine
  4. Psoriasis
  5. Eruption
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Pharmaco Atlas

Most Correlated Compounds

  1. PF 3758309
  2. AT 7519
  3. MK 1775
  4. KIN001-260
  5. BGT-226
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. TIRAP
  2. HOXA6
  3. GNB1
  4. ACLY
  5. MIR16-2
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Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Breast adenocarcinoma SKBR3 cells treated with small molecule perturbagens
  2. L1000 CMAP - Neuronal NEU cells treated with small molecule perturbagens
  3. L1000 CMAP - Carcinoma of prostate PC3 cells treated with ligand perturbagens
  4. L1000 CMAP Prostate cancer VCaP cells with gene overexpression perturbations
  5. L1000 CMAP Colorectal cancer HT 29 cells with gene overexpression perturbations
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Literature

Most Relevant Literature

  1. A rare variant at the KYNU gene is associated with kynureninase activity and essential hypertension …
  2. Structure, mechanism, and substrate specificity of kynureninase.
  3. Tryptophan metabolism along the kynurenine pathway in diet-induced and genetic hypercholesterolemic …
  4. Peripheral distribution of kynurenine metabolites and activity of kynurenine pathway enzymes in rena…
  5. Effects of mitochondria and o-methoxybenzoylalanine on 3-hydroxyanthranilic acid dioxygenase activit…
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Clinical Trials

Most Relevant Clinical Trials

  1. Assesment of Vitamin B6 Level in Patients With Major Depressive Disorder
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