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mdv 3100
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
KLK2
ST6GALNAC1
KLK3
CHRNA2
TRPM8
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Pathway Enrichment
Most Correlated Biogroups
FISCHER_DREAM_TARGETS
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP
DODD_NASOPHARYNGEAL_CARCINOMA_DN
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP
LEE_BMP2_TARGETS_DN
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Curated Studies
Most Correlated Studies
Transcriptional responses of control and MDV3100 resistant lines to DMSO or MDV3100
Resistance to anti-androgens in prostate cancer cell lines and xenografts
Prostate cancer cell lines treated with BET domain inhibitors
Prostate cancer CWR-R1, LAPC-4, LNCaP and VCAP cells treated with Enzalutamide
Prostate carcinoma LNCaP cells treated with dihydrotestosterone and enzalutamide
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Literature
Most Relevant Literature
Enhanced antitumor efficacy by combining afatinib with MDV3100 in castration-resistant prostate canc…
Influence of Androgen Receptor Antagonist MDV3100 Therapy on Rats With Benign Prostatic Hyperplasia.
Abiraterone and MDV3100 inhibits the proliferation and promotes the apoptosis of prostate cancer cel…
MDV3100: Tritium labeling at high specific activity.
Characterization of a novel p110β-specific inhibitor BL140 that overcomes MDV3100-resistance in cast…
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Clinical Trials
Most Relevant Clinical Trials
Sodium Fluoride (NaF) Positron Emission Tomography/Computed Tomography (PET/CT) in Patients With Met…
NaF Positron Emission Tomography/Computed Tomography (PET/CT)Imaging to Assess Treatment Responsiven…
Linsitinib in Treating Patients With Asymptomatic or Mildly Symptomatic Metastatic Prostate Cancer
A Multicenter Phase I/II Trial of Abiraterone Acetate + BEZ235 in Metastatic, Castration-Resistant P…
Tivozanib + Enzalutamide in Adv Prostate Cancer
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