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midostaurin
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
NR1D1
gch2
per1a
zgc:112992
zgc:56382
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Pathway Enrichment
Most Correlated Biogroups
heterocyclic compound binding
organic cyclic compound binding
organic cyclic compound metabolic process
cellular aromatic compound metabolic process
heterocycle metabolic process
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Curated Studies
Most Correlated Studies
Embryonic gene expression in response to the antineoplastic agent PKC412
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
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Literature
Most Relevant Literature
Clinically relevant bidirectional drug-drug interaction between midostaurin and voriconazole.
Case Report: Molecular and microenvironment change upon midostaurin treatment in mast cell leukemia …
Effect of flavonoids and CYP3A4 variants on midostaurin metabolism.
Indirect treatment comparisons of avapritinib versus midostaurin for patients with advanced systemic…
Superior Efficacy of Midostaurin Over Cladribine in Advanced Systemic Mastocytosis: A Registry-Based…
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Clinical Trials
Most Relevant Clinical Trials
Midostaurin in Indolent Systemic Mastocytosis
PK and Safety of Midostaurin in Subjects With Impaired Hepatic Function and Subjects With Normal Hep…
Cladribine Based Induction Therapy With All-Trans Retinoic Acid and Midostaurin in Relapsed/Refracto…
Phase I Combination of Midostaurin, Bortezomib, and Chemo in Relapsed/Refractory Acute Myeloid Leuke…
Gilteritinib vs Midostaurin in FLT3 Mutated Acute Myeloid Leukemia
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