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mk 5108
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Summary
General Info
Genetic Markers
Most Correlated Genes
No genes found
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Pathway Enrichment
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Curated Studies
Most Correlated Studies
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
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Literature
Most Relevant Literature
Blocking AURKA with MK-5108 attenuates renal fibrosis in chronic kidney disease.
Preclinical evaluation of the Aurora kinase inhibitors AMG 900, AZD1152-HQPA, and MK-5108 on SW-872 …
A phase I study of MK-5108, an oral aurora a kinase inhibitor, administered both as monotherapy and …
Anticancer activity of the Aurora A kinase inhibitor MK-5108 in non-small-cell lung cancer (NSCLC) i…
Apoptosis is responsible for the cytotoxic effects of anti-GD2 ganglioside antibodies and aurora A k…
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Clinical Trials
Most Relevant Clinical Trials
Treatment of Participants With Advanced and/or Refractory Solid Tumors (MK-5108-001)
Follow-Up Study for Exubera
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