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neratinib
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
EGR1
AKAP12
TXNIP
HAL
CPVL
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Pathway Enrichment
Most Correlated Biogroups
organic cyclic compound binding
heterocyclic compound binding
regulation of nitrogen compound metabolic process
cytosol
organic cyclic compound metabolic process
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Curated Studies
Most Correlated Studies
Bladder cancer and ovarian cancer parental or neratinib-resistant cells treated with neratinib
Multiple cancer cell lines treated with 32 kinase inhibitors
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
L1000 CMAP - Hepatocellular carcinoma HEPG2 cells treated with small molecule perturbagens
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Literature
Most Relevant Literature
Effects of orally administered crofelemer on the incidence and severity of neratinib-induced diarrhe…
Neratinib for HER2-positive breast cancer with an overlooked option.
Neratinib as adjuvant therapy in patients with HER2 positive breast cancer: expert opinion.
Development of a Validated UPLC-MS/MS Method for Simultaneous Estimation of Neratinib and Curcumin i…
Targeting HER2-mutant metastatic cervical cancer with neratinib: Final results from the phase 2 SUMM…
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Clinical Trials
Most Relevant Clinical Trials
Fulvestrant + Neratinib In Breast Cancer
Real-life Pan-HER-blockade With Neratinib
Open-label PK Study to Evaluate Lansoprazole and Neratinib in Healthy Subjects
A Study Of Neratinib (HKI-272) And Capecitabine In Japanese With Solid Tumor
Neratinib +/- Fulvestrant in HER2+, ER+ Metastatic Breast Cancer
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