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nordihydroguaiaretic acid
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
PTGS1
PTGS2
ALOX15
DNAJB9
GCLM
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Pathway Enrichment
Most Correlated Biogroups
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP
nuclear outer membrane-endoplasmic reticulum membrane network
lipid biosynthetic process
WINTER_HYPOXIA_METAGENE
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP
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Curated Studies
Most Correlated Studies
Drug target sets for approved compounds
Broad Connectivity Map (CMAP 2.0) compound database
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
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Literature
Most Relevant Literature
Larvicidal activity of crude extracts from Larrea cuneifolia (Zygophyllaceae) and of its metabolite …
Effects of nordihydroguaiaretic acid on in vitro fermentation profiles of rumen bacteria.
The dietary supplementation of nordihydroguaiaretic acid (NDGA) delayed the loss of climbing ability…
Molecular mechanisms and clinical applications of nordihydroguaiaretic acid (NDGA) and its derivativ…
mTORC1 is a target of nordihydroguaiaretic acid to prevent breast tumor growth in vitro and in vivo.
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Clinical Trials
Most Relevant Clinical Trials
Nordihydroguaiaretic Acid in Treating Patients With Nonmetastatic Relapsed Prostate Cancer
Tetra-O-Methyl Nordihydroguaiaretic Acid in Treating Patients With Recurrent High-Grade Glioma
Pharmacokinetic and Efficacy Study of Nordihydroguaiaretic Acid (NDGA) in Non Metastatic Recurrent P…
A Pilot Study of EM-1421 for the Treatment of Cervical Intraepithelial Neoplasia
Study of Intralesional Injection of M4N in Patients With Refractory Malignant Tumors of the Head and…
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