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osteolytic lesions
(phenotype)
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Genetic Markers
Most Correlated Genes
Most Correlated SNPs
TNFRSF11A
MMP2
No SNPs found
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Pathway Enrichment
Most Correlated Biogroups
GSE16450_CTRL_VS_IFNA_12H_STIM_IMMATURE_NEURON_CELL_LINE_DN
GSE22935_WT_VS_MYD88_KO_MACROPHAGE_UP
ossification
72kDa type IV collagenase
Tumour necrosis factor receptor 11A
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Curated Studies
Most Correlated Studies
Bone marrow from multiple myeloma patients with and without lytic lesions
OMIM - Disease of bone
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Literature
Most Relevant Literature
Multicentric carpotarsal osteolysis syndrome with variants of MAFB gene: a case report and literatur…
Mechanism of regulating macrophages/osteoclasts in attenuating wear particle-induced aseptic osteoly…
Medication-related osteonecrosis of the lower jaw without osteolysis on computed tomography images.
A Unique Case of Familial Expansile Osteolysis: Findings on 99mTc-MDP Bone Scan.
Britanin inhibits titanium wear particle‑induced osteolysis and osteoclastogenesis.
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Clinical Trials
Most Relevant Clinical Trials
A Safety, Tolerability and Efficacy Study of ACE-011 in Patients With Osteolytic Lesions of Multiple…
Efficacy and Tolerability of Zoledronic Acid With Radiotherapy in Pts With Advanced Osteolytic Bone …
Effect of Denosumab on Inflammatory Osteolytic Lesion Activity in Total Hip Arthroplasty
Open-label Study, to Evaluate the Safety and Tolerability of Zoledronic Acid in Patients With Bone L…
Bisphosphonate-Associated Jaw Osteonecrosis and PET Imaging
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