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osteosclerosis
(phenotype)
Summary
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Genetic Markers
Most Correlated Genes
Most Correlated SNPs
LRP5
No SNPs found
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Pathway Enrichment
Most Correlated Biogroups
Low density lipoprotein receptor-related protein 5/6
coreceptor activity involved in canonical Wnt signaling pathway
Wnt signaling pathway involved in dorsal/ventral axis specification
Wnt-Frizzled-LRP5/6 complex
apoptotic process involved in blood vessel morphogenesis
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Curated Studies
Most Correlated Studies
Skin biopsies from patients with ichthyosis subtypes
OMIM - Trichodontoosseous syndrome
OMIM - Skeletal dysplasia
Mouse Phenotypes - Dwarfism
OMIM - Disease of bone
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Literature
Most Relevant Literature
Neurological manifestations in patients and disease carriers in an Italian family with osteosclerosi…
The Osteosclerosis Challenge: Toothpaste Unveiling Secrets.
Metformin alleviates osteoarthritis in mice by inhibiting chondrocyte ferroptosis and improving subc…
Automated Osteosclerosis Grading of Clinical Biopsies Using Infrared Spectroscopic Imaging.
Inhibition of interleukin-1β reduces myelofibrosis and osteosclerosis in mice with JAK2-V617F driven…
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Most Relevant Clinical Trials
Bortezomib in Treating Patients With Advanced Myeloproliferative Disorders
PsA Secukinumab XCT Structural Progression Study
Effects of Achieving SDAI Remission on Joint Space Outcomes Progression in Early Rheumatoid Arthriti…
Optimization of Total Knee Arthroplasty Using Robotic Systems
Canalith Repositioning Procedure for BPPV in Primary Care
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