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parp1 protein, human
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Genetic Markers
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Curated Studies
Most Correlated Studies
Expression Analysis Upon PARP-1 or PARG Knockdown in MCF-7 Cells
Cervical cancer HeLa cells with PARP-1 siRNA knockdown
PARP-1 KO and wild type T cells following CD3 and CD3/CD28 activation
Burkitt lymphoma DG-75 cells expressing EBV LMP1 and treated with olaparib
Hepatocellular carcinoma HepG2 cells with siRNA knockdown of the nuclear protein WEE1
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Literature
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Loss of cytidine deaminase expression as a potential attempt to counteract the process of carcinogen…
From Serendipity to Intention: Development of Brain-Penetrant PARP1-Selective Inhibitors.
Poly (ADP-ribose) Polymerase-1 modulations in the genesis of thrombosis.
Unraveling the allosteric inhibition mechanism of PARP-1 CAT and the D766/770A mutation effects via …
PARP1-DNA co-condensation drives DNA repair site assembly to prevent disjunction of broken DNA ends.
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Clinical Trials
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Nivolumab in Combination With Talazoparib in Melanoma and Mutations in BRCA or BRCA-ness Genes
Pamiparib Plus Surufatinib in Patients With Platinum-resistant Ovarian Cancer
Preoperative Olaparib Endometrial Carcinoma Study (POLEN)
Study of Gemcitabine, Carboplatin and VELIPARIB (ABT-888) in Refractory Testicular Germ Cell Cancer
Cabozantinib and Pamiparib for the Treatment of Advanced of Refractory Solid Tumors
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