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QuickView for patupilone (compound)


Genetic Markers

Most Correlated Genes

  1. CRIP1
  2. ANO1
  3. DLK1
  4. TXNIP
  5. LPL
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Pathway Enrichment

Most Correlated Biogroups

  1. cytosol
  2. organic cyclic compound binding
  3. heterocyclic compound binding
  4. regulation of nitrogen compound metabolic process
  5. organic cyclic compound metabolic process
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Curated Studies

Most Correlated Studies

  1. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
  2. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
  3. L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
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Literature

Most Relevant Literature

  1. An efficient total synthesis of (-)-epothilone B.
  2. Use of epothilone B (patupilone) in refractory lymphoma and advanced solid tumors in dogs.
  3. Patupilone and ixabepilone: the effect of a point structural change on the exo-endo conformational p…
  4. Patupilone (epothilone B) for recurrent glioblastoma: clinical outcome and translational analysis of…
  5. Novel physiologically based pharmacokinetic modeling of patupilone for human pharmacokinetic predict…
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Clinical Trials

Most Relevant Clinical Trials

  1. Phase I Study of Patupilone and RAD001
  2. Patupilone (EPO 906) in Patients With Recurrent or Progressive Glioblastoma
  3. Efficacy and Safety of Patupilone in Patients With Advanced Solid Tumors in Japan
  4. The Effects of Patupilone on the Pharmacokinetics and Pharmacodynamics of Warfarin in Patients With …
  5. Evaluate the Effects of Patupilone on the Pharmacokinetics of Midazolam and Omeprazole in Patients W…
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