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QuickView for pd98059 (compound)


Genetic Markers

Most Correlated Genes

  1. DMKN
  2. CDH1
  3. MGST1
  4. CD36
  5. TDGF1
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Pathway Enrichment

Most Correlated Biogroups

  1. KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP
  2. FISCHER_DREAM_TARGETS
  3. DODD_NASOPHARYNGEAL_CARCINOMA_DN
  4. RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP
  5. JOHNSTONE_PARVB_TARGETS_3_DN
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Curated Studies

Most Correlated Studies

  1. Breast cancer Py2T cells treated with BMP2 and MEK inhibitor PD98059
  2. Colorectal cancer cell lines treated with inhibitors of signaling pathway effectors
  3. Induced pluripotent stem cells gene profiling in induction and withdrawal of 5 reprogramming factors
  4. Jurkat T cells activated with CD3, CD28 and PMA and multiple kinase inhibitors
  5. MDCK cells treated with hepatocyte growth factor and MAPK ERK pathway inhibitors
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Literature

Most Relevant Literature

  1. Endothelial dysfunction caused by circulating microparticles from diabetic mice is reduced by PD9805…
  2. Paclitaxel anticancer activity is enhanced by the MEK 1/2 inhibitor PD98059 in vitro and by PD98059-…
  3. The MAP kinase inhibitor PD98059 reduces chromosomal instability in the autoimmune encephalomyelitis…
  4. An injectable microparticle formulation for the sustained release of the specific MEK inhibitor PD98…
  5. PD98059 Protects Cerebral Cortex Mitochondrial Structure and Function at 48 h Post-Resuscitation in …
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Clinical Trials

Most Relevant Clinical Trials

  1. Study the Expression of Annexin A1 and Its Potential Usage as a Prognostic Marker in Oral Cancer
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