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polo like kinase 1
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Curated Studies
Most Correlated Studies
Neuroblastoma SK-N-AS cells after PLK1 inhibitor GSK461364 treatment
Erythroid cells with shRNA-mediated SF3B1 knockdown
Androgen-independent prostate carcinoma PC-3 cells treated with menthol
Head and neck squamous cell carcinoma cell lines resistant or sensitive to rigosertib
BMDCs treated with BI2536 or vehicle control and stimulated with LPS or poly(I:C)
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Most Relevant Literature
RPL27 contributes to colorectal cancer proliferation and stemness via PLK1 signaling.
Age-related SUMOylation of PLK1 is essential to meiosis progression in mouse oocytes.
Vaccinia-related kinase 2 drives pancreatic cancer progression by protecting Plk1 from Chfr-mediated…
BI6727 and GSK461364A, potent PLK1 inhibitors induce G2/M arrest and apoptosis against cholangiocarc…
Hornerin mediates phosphorylation of the polo-box domain in Plk1 by Chk1 to induce death in mitosis.
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Clinical Trials
Most Relevant Clinical Trials
Phosphoproteomic Patterns as a Novel Biomarker for Aurora and Polo-like Kinase Inhibitors in Non-Sma…
A Phase I Study of CYC140, a PLK-1 Inhibitor, in Advanced Leukemias or MDS
A Study of Volasertib Plus Induction Chemotherapy for Acute Myeloid Leukemia
Study of NMS-1286937 in Adult Patients With Advanced/Metastatic Solid Tumors
Study of PLK1 Inhibitor, Onvansertib, in Relapsed Small Cell Lung Cancer
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