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QuickView for polymyxin e (compound)


Genetic Markers

Most Correlated Genes

  1. MBL1P
  2. UBR2
  3. GHR
  4. EGR1
  5. KCNH6
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Pathway Enrichment

Most Correlated Biogroups

  1. DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP
  2. response to extracellular stimulus
  3. SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN
  4. GSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_12H_UP
  5. response to organic substance
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Curated Studies

Most Correlated Studies

  1. Liver Pharmacology and Xenobiotic Response Repertoire
  2. Kidneys from C57BL6 mice treated intraperitoneally with colistin sulfate
  3. Drug Matrix In Vivo Toxicogenomic Study - Rat Liver [Codelink]
  4. Broad Connectivity Map (CMAP 2.0) compound database
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Literature

Most Relevant Literature

  1. Colistin Resistance in Multidrug-Resistant Escherichia coli Isolated from Retail Broiler Meat in Ban…
  2. Azomycin Orchestrate Colistin-Resistant Enterobacter cloacae Complex's Colistin Resistance Reversal …
  3. Plasmid-mediated colistin-resistance genes: mcr.
  4. Mobile colistin resistance (mcr) genes and recent developments in colistin resistance detection.
  5. Metabolic engineering of "last-line antibiotic" colistin in Paenibacillus polymyxa.
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Clinical Trials

Most Relevant Clinical Trials

  1. Optimizing Clinical Use of Polymyxin B
  2. Melatonin for Renal Protection in Patients Receiving Polymyxin B
  3. A Pharmacokinetic Study of Polymyxin B in Healthy Subjects and Subjects With Renal Insufficiency
  4. Polymyxin B Monotherapy vs Combination Therapy in Critically Ill Patients With Multi-drug Resistant …
  5. Early Use of Polymyxin B Hemoperfusion in Abdominal Sepsis
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