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Correlation Engine 2.0
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(e.g. Pharmacogenetics, Doxorubicin, rs7903146, CYP51, G-protein-coupled receptor binding)
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QuickView for polyposis coli (phenotype)


Genetic Markers

Most Correlated Genes

Most Correlated SNPs

  1. APC
  2. RNF43
  3. CA1
  4. SLC26A3
  5. MS4A12
  1. No SNPs found
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Pathway Enrichment

Most Correlated Biogroups

  1. regulation of nitrogen compound metabolic process
  2. organic cyclic compound binding
  3. heterocyclic compound binding
  4. DODD_NASOPHARYNGEAL_CARCINOMA_DN
  5. PUJANA_BRCA1_PCC_NETWORK
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Curated Studies

Most Correlated Studies

  1. OMIM - Congenital disorder
  2. Intestinal tumors from KRas mutant Apc1638N mice; sorted for cancer stem cell fraction
  3. Large intestinal cells from familial adenomatous polyposis subjects
  4. Colonic organoids from iPSC of familial adenomatous polyposis patients with APC mutations
  5. Colonic tubular adenoma from patients with lynch syndrome or with familial adenomatous polyposis
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Literature

Most Relevant Literature

  1. Wnt-Independent and Wnt-Dependent Effects of APC Loss on the Chemotherapeutic Response.
  2. The 15-Amino Acid Repeat Region of Adenomatous Polyposis Coli Is Intrinsically Disordered and Retain…
  3. Conformational Selection Mechanism Provides Structural Insights into the Optimization of APC-Asef In…
  4. Association of APC gene promoter methylation and the risk of gastric cancer: A meta-analysis and bio…
  5. A novel large germ line deletion in adenomatous polyposis coli (APC) gene associated with familial a…
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Clinical Trials

Most Relevant Clinical Trials

  1. Chemoprevention Trial in Familial Adenomatous Polyposis (FAP) Coli Using EPA
  2. Niclosamide for Familial Adenomatous Polyposis
  3. A Study of Guselkumab in Participants With Familial Adenomatous Polyposis
  4. Primary Chemoprevention of Familial Adenomatous Polyposis With Berberine Hydrochloride
  5. Endoscopic Evaluation of Duodenal Polyposis in Patients With Familial Adenomatous Polyposis (FAP)
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