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r 848
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
IFNB1
CCL5
CXCL11
TNFAIP6
CXCL3
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Pathway Enrichment
Most Correlated Biogroups
GSE2706_UNSTIM_VS_2H_LPS_AND_R848_DC_DN
GSE2706_UNSTIM_VS_2H_R848_DC_DN
GSE2706_UNSTIM_VS_2H_LPS_DC_DN
GSE9988_ANTI_TREM1_VS_LOW_LPS_MONOCYTE_DN
GSE9988_ANTI_TREM1_VS_ANTI_TREM1_AND_LPS_MONOCYTE_DN
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Curated Studies
Most Correlated Studies
Toll like receptor (TLR) agonists on human dendritic cells
Resiquimod Treatment and the Asthma Transcriptome
Granulocytes from HL-60 APML cells with POU2F2 siRNA knockdown and treated with R848
Dendritic cells from monocytes of healthy donors treated with HMGN1, R848 or both
Monocytes pretreated with IRAK4 inhibitor PF-06426779 followed by treatment with TLR7/8 agonist R848
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Literature
Most Relevant Literature
Anti-melanoma Effects of Resiquimod (RSQ) In Vitro and in Combination with Immune Checkpoint Blockad…
Investigating silver nanoparticles and resiquimod as a local melanoma treatment.
Radiation-Activated Resiquimod Prodrug Nanomaterials for Enhancing Immune Checkpoint Inhibitor Thera…
Azide-Masked Resiquimod Activated by Hypoxia for Selective Tumor Therapy.
Carboxymethylated Alginate-Resiquimod Micelles Reverse the Immunosuppressive Tumor Microenvironment …
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Clinical Trials
Most Relevant Clinical Trials
Preliminary Safety and Tolerability of CD19x22 CAR T Cells in Adolescent and Adult R/R B-NHL Patient…
Study of Zevalin Versus Observation in Patients at Least 60 Yrs Old With Newly Diagnosed Diffuse Lar…
A Study of Pembrolizumab (MK-3475) With or Without Lenvatinib (E7080/MK-7902) as First Line (1L) Int…
Impact of Aging on Cytokine Production by Innate Immune Cells
Intradermal Trivalent Influenza Vaccine With Imiquimod
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