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rad50 protein, s pombe
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The fission yeast MRN complex tethers dysfunctional telomeres for NHEJ repair.
The fission yeast Rad32(Mre11)-Rad50-Nbs1 complex acts both upstream and downstream of checkpoint si…
Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous r…
Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair.
Ctp1 and the MRN-complex are required for endonucleolytic Rec12 removal with release of a single cla…
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