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small hairpin rna
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Summary
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Genetic Markers
Most Correlated Genes
MIR30A
CRYAB
MFAP4
IFIT2
SHH
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Pathway Enrichment
Most Correlated Biogroups
response to organic substance
NUYTTEN_EZH2_TARGETS_UP
MURARO_PANCREAS_DUCTAL_CELL
DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN
response to stress
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Curated Studies
Most Correlated Studies
Glioblastoma-derived cancer stem cell neurospheres expressing off-target GNL3 shRNA
Liver expression profiles after expressing anti-HCV shRNAs
Articular chondrocyte C-28I2 cells with shRNA mediated CA2 knockdown
Cervical carcinoma HeLa cells with CRISPR-CAS13d mediated targeting of DMPK CUG repeat
CD4 T-cells with MTOR, ZAP70 silencing, or treated with Rapamycin or Cyclosporin A
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Literature
Most Relevant Literature
Uncovering hidden cancer self-dependencies through analysis of shRNA-level dependency scores.
Preparation and Use of shRNA for Knocking Down Specific Genes.
Evaluation of the Elements of Short Hairpin RNAs in Developing shRNA-Containing CAR T Cells.
Intranasal delivery of shRNA to knockdown the 5HT-2A receptor enhances memory and alleviates anxiety…
Photo-dependent cytosolic delivery of shRNA into a single blastomere in a mouse embryo.
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Clinical Trials
Most Relevant Clinical Trials
Gene Transfer for Sickle Cell Disease
Lapatinib and RAD-001 for HER2 Positive Metastatic Breast Cancer
Evaluating Safety and Efficacy of Tivozanib (AV-951) in Cholangiocarcinoma
Norovirus Challenge Study
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