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spastic paraplegia
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Summary
General Info
Genetic Markers
Most Correlated Genes
Most Correlated SNPs
SPG16
BSCL2
SPOAN
SPG34
ATP5MC3
No SNPs found
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Pathway Enrichment
Most Correlated Biogroups
GSE12845_IGD_NEG_BLOOD_VS_NAIVE_TONSIL_BCELL_UP
NUYTTEN_EZH2_TARGETS_DN
GSE15330_HSC_VS_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_DN
GSE22886_DAY1_VS_DAY7_MONOCYTE_IN_CULTURE_DN
GCM_NCAM1
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Curated Studies
Most Correlated Studies
Mouse Phenotypes - Disorder of extremity
Comparative profiling in 13 muscle disease groups
OMIM - Nervous system disorders
OMIM - Neuropathy
OMIM - Spastic Ataxias
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Literature
Most Relevant Literature
A Homoplasmic MT-TV Mutation Associated with Mitochondrial Inheritance of Hereditary Spastic Paraple…
Hereditary spastic paraplegias proteome: common pathways and pathogenetic mechanisms.
Biallelic variants in the COQ4 gene caused hereditary spastic paraplegia predominant phenotype.
Biallelic COQ4 Variants in Hereditary Spastic Paraplegia: Clinical and Molecular Characterization.
ARL6IP1 gene delivery reduces neuroinflammation and neurodegenerative pathology in hereditary spasti…
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Clinical Trials
Most Relevant Clinical Trials
Physiotherapy in Hereditary Spastic Paraplegia
A Registered Cohort Study on Spastic Paraplegia
Effects of Botulinum Toxin Injections in Patients With Hereditary Spastic Paraplegia
Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia
Identification of Modifying Factors in Hereditary Spastic Paraplegia
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