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sulfonylurea compounds
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
CYP51A1
FABP4
PPP2CA
FOS
DLX5
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Pathway Enrichment
Most Correlated Biogroups
PILON_KLF1_TARGETS_DN
organic cyclic compound metabolic process
heterocycle metabolic process
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP
organic cyclic compound binding
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Curated Studies
Most Correlated Studies
Hepatocellular carcinoma HepG2 cells treated with hepatotoxic or non-hepatotoxic compounds
Hepatoma cells, hepatocellular carcinoma cells, and induced hepatocytes treated with carcinogens
Hepatocytes conventionally cultured or trichostatin A-stabilized treated with hepatocarcinogens
B-cell lymphoma cell lines treated by 92 FDA approved compounds - a timecourse
Drug Matrix In Vivo Toxicogenomic Study - Rat Liver [Affymetrix]
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Literature
Most Relevant Literature
Chemical synthesis, biological activities, and molecular simulations of novel sulfonylurea compounds…
Discovery of ortho-Alkoxy Substituted Novel Sulfonylurea Compounds That Display Strong Herbicidal Ac…
Targeting NLRP3 signaling by a novel-designed sulfonylurea compound for inhibition of microglial inf…
Structure-based design and synthesis of sulfonylureas as novel NLRP3 inhibitors for Alzheimer's dise…
G004, a synthetic sulfonylurea compound, exerts anti-atherosclerosis effects by targeting SIRT1 in A…
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Clinical Trials
Most Relevant Clinical Trials
Long-Term Sulfonylurea Response in KCNJ11 Neonatal Diabetes
Long-Term Sulfonylurea Response in ABCC8 Neonatal Diabetes (SuResponsSUR)
A Study to Assess the Efficacy and Safety of ASP1941 in Combination With Sulfonylurea in Type 2 Diab…
The Beta Cell Responsiveness to Glucose-dependent Insulinotropic Polypeptide (GIP) With and Without …
Effectiveness and Safety of Adding Compound Preparation of Pioglitazone and Metformin for Type 2 Dia…
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