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QuickView for tiopronin (compound)


Genetic Markers

Most Correlated Genes

  1. ITSN2
  2. DUSP1
  3. RGD1309362
  4. GPATCH4
  5. LPIN1
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Pathway Enrichment

Most Correlated Biogroups

  1. PILON_KLF1_TARGETS_DN
  2. heterocyclic compound binding
  3. GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN
  4. organic cyclic compound binding
  5. nucleoplasm
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Curated Studies

Most Correlated Studies

  1. Genomics Assisted Toxicity Evaluation system study - Human Hepatocytes
  2. Genomics Assisted Toxicity Evaluation system study - Rat Liver Single Dose
  3. Genomics Assisted Toxicity Evaluation system study - Rat Liver Repeat Doses
  4. Genomics Assisted Toxicity Evaluation system study - Rat Hepatocytes
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Literature

Most Relevant Literature

  1. Evaluate the value of prolonging the duration of tiopronin for injection administration in preventin…
  2. Cytotoxic Activity of Unique Synthesized Five-membered Heterocyclic Compounds Coordinated with Tiopr…
  3. Chemical Modification of Tiopronin for Dual Management of Cystinuria and Associated Bacterial Infect…
  4. Tiopronin-induced membranous nephropathy in a patient with refractory familial cystinuria.
  5. Mycoplasma Infection Mediates Sensitivity of Multidrug-Resistant Cell Lines to Tiopronin: A Cautiona…
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Clinical Trials

Most Relevant Clinical Trials

  1. Effect of Increasing Doses of Tiopronin on Cystine Capacity in Patients With Cystinuria
  2. The Effects of Tiopronin on 3-Aminopropanal Level & Neurologic Outcome After Aneurysmal Subarachnoid…
  3. Effect of Increasing Doses of Cystine Binding Thiol Drugs on Cystine Capacity in Patients With Cysti…
  4. Efficacy and Safety Study of Magnesium Isoglycyrrhizinate Injection in Subjects With Acute Drug-indu…
  5. Bucillamine Phase 2 Trial in Patients With Cystinuria
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