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topoisomerase I
(compound)
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Genetic Markers
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Curated Studies
Most Correlated Studies
Gastroesophegeal tumors and adjacent normal tissues before and after chemotreatment
Colon cancer HT 115 cells expressing UGT1A isoform 2 shRNA and treated with SN-38
Diffuse Large B-Cell Lymphoma OCI-LY3 cells time-course/dose response treatment with 14 drug panel
Metastatic colorectal tumors from responder and nonresponder patients undergoing the FOLFIRI regimen
Colorectal cancer liver metastases, primary tumors and prospective response to FOLFIRI chemotherapy
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Literature
Most Relevant Literature
Chemical mutagenesis of vaccinia DNA topoisomerase lysine 167 provides insights to the catalysis of …
Structural and functional interactions of the prostate cancer suppressor protein NKX3.1 with topoiso…
Metal ion and inter-domain interactions as functional networks in E. coli topoisomerase I.
Specific detection of topoisomerase I from the malaria causing P. falciparum parasite using isotherm…
A pentapeptide signature motif plays a pivotal role in Leishmania DNA topoisomerase IB activity and …
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Clinical Trials
Most Relevant Clinical Trials
Clinical Benefit of Topoisomerase Downregulation
Topoisomerase II Alpha Gene Amplification and Protein Overexpression Predicting Efficacy of Epirubic…
Study of Sequential Topoisomerase, Irinotecan/Oxaliplatin - Etoposide /Carboplatin in Extensive Smal…
Phase I Study of Intrathecal Topotecan
Phase I/II Trial of Valproic Acid and Karenitecin for Melanoma
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